The ubiquitous role of nitric oxide in cardioprotection. Wekking EM, Appelhof BC, Fliers E, Schene AH, Huyser J, Tijssen JG, Wiersinga WM.2005, Cognitive functioning and well-being in euthyroid patients on thyroxine replacement therapy for primary hypothyroidism, Thyroid hormone replacement: an iatrogenic problem, Carr D, McLeod DT, Parry G, Thornes HM.1988, Fine adjustment of thyroxine replacement dosage: comparison of the thyrotrophin releasing hormone test using a sensitive thyrotrophin assay with measurement of free thyroid hormones and clinical assessment, Ott J, Promberger R, Kober F, Neuhold N, Tea M, Huber JC, Hermann M.2011, Hashimoto's thyroiditis affects symptom load and quality of life unrelated to hypothyroidism: a prospective case-control study in women undergoing thyroidectomy for benign goiter, Pop VJ, Maartens LH, Leusink G, van Son MJ, Knottnerus AA, Ward AM, Metcalfe R, Weetman AP.1998. 2015;14(3):271-80. Am J Epidemiol. View abstract. In this setting, primary hypothyroidism may itself be the inciting cause of critical illness or might complicate a nonthyroidal critical illness if unrecognized and untreated (603). 1a. Although the impact of multivitamins on LT4 absorption does not appear to have been studied, their calcium and ferrous salt content would be expected to result in impaired absorption. 217, No. J Natl Cancer Inst 2000;92:780-1. It can bind to the T3 receptor and it can decrease TSH secretion. The founder and CEO of AJ Crimson Beauty, AJ Crimson, has passed away recently. Similarly, effects of polymorphisms in TH transporters on transport function and thus tissue T3 levels have not been reported. Development of myocardial fibrosis in diabetic cardiomyopathy involves the deposition of stiff collagen and its cross-linking, cardiac interstitial fibrosis, progressive abolition of muscular fibrils, perivascular fibrosis, thickened and sclerotic small coronary vessels, and basement membrane thickening, as well as coronary microvascular sclerosis and microaneurysms.33,34 Activation of the RAAS and SNS, stimulation of advanced glycation end products (AGE)mediated signaling via cell surface receptor for AGE (RAGE), hyperinsulinemia, and hyperglycemia collectively lead to activation of transforming growth factor 1 pathway and dysregulation of extracellular matrix degradation.35 Some biomarkers of collagen synthesis, including inflammation cytokines, connective tissue growth factor, metalloproteinases, and galectin-3, can be used clinically in the determination of myocardial fibrosis.36 As discussed in more detail later, reduced bioavailable NO, increased oxidative stress, and an activated transforming growth factor 1/SMAD signaling pathway, in concert with impaired insulin metabolic signaling pathways, increase the myocardial fibronectin and collagen content and cardiac interstitial fibrosis characteristic of diabetic cardiomyopathy.17. J Drugs Dermatol. Anecdotal reports have suggested that LT4 therapy may be useful in the treatment of urticaria in euthyroid individuals with positive thyroid autoantibodies [e.g., Monge et al. Information needs identified by stakeholders at this meeting were incorporated in task force group decisions in considering topics for review. Vitamin A improves the symptoms of autism spectrum disorders and decreases 5-hydroxytryptamine (5-HT): A pilot study. With T3 monotherapy, multiple daily dosing is required to sustain serum T3 levels due to the shorter half-life of LT3, compared with LT4 (348). View abstract. 1, 5 February 2018 | Journal of Translational Medicine, Vol. Bu Q, Li S. The curative effect of Astragalus injection for aged patients with congestive heart failure. Databases searches were generally updated at least once. For patients with subclinical hypothyroidism and thyrotropin >10mIU/L with signs and symptoms consistent with primary thyroid disease and/or risk factors associated with progression, levothyroxine replacement may be reasonable. Arch Dermatol 2007;143(5):606-12. There are case reports demonstrating death without treatment (600602). View abstract. [22][19]:3132 Common Sense made a persuasive, impassioned case for independence, which had not been given serious consideration in the colonies. Note that the opening lines differ between the two versions. Ramakrishnan U., Nguyen P., Martorell R. Effects of micronutrients on growth of children under 5 y of age: meta-analyses of single and multiple nutrient interventions. "He has refused for a long time, after such dissolutions, to cause others to be elected, whereby the Legislative Powers, incapable of Annihilation, have returned to the People at large for their exercise; the State remaining in the meantime exposed to all the dangers of invasion from without, and convulsions within. McDonald, "Jefferson's Reputation", 172, 179. [9]:82 The inspiration and content of the French Declaration of the Rights of Man and of the Citizen (1789) emerged largely from the ideals of the American Revolution. These include the Haitian declaration of January 1, 1804 during the Haitian Revolution, the United Provinces of New Granada in 1811, the Argentine Declaration of Independence in 1816, the Chilean Declaration of Independence in 1818, Costa Rica in 1821, El Salvador in 1821, Guatemala in 1821, Honduras in 1821, Mexico in 1821, Nicaragua in 1821, Peru in 1821, Bolivian War of Independence in 1825, Uruguay in 1825, Ecuador in 1830, Colombia in 1831, Paraguay in 1842, Dominican Republic in 1844, Texas Declaration of Independence in March 1836, California Republic in November 1836, Hungarian Declaration of Independence in 1849, Declaration of the Independence of New Zealand in 1835, and the Czechoslovak declaration of independence from 1918 drafted in Washington D.C. with Gutzon Borglum among the drafters. Chen, H., Zhuo, Q., Yuan, W., Wang, J., and Wu, T. Vitamin A for preventing acute lower respiratory tract infections in children up to seven years of age. Lawson, L., Thacher, T. D., Yassin, M. A., Onuoha, N. A., Usman, A., Emenyonu, N. E., Shenkin, A., Davies, P. D., and Cuevas, L. E. Randomized controlled trial of zinc and vitamin A as co-adjuvants for the treatment of pulmonary tuberculosis. Van, D. E., Kulier, R., Gulmezoglu, A. M., and Villar, J. Vitamin A supplementation during pregnancy. [25] How these increased levels of catecholamines act in the body to produce the changes seen with TTS is not clearly understood. J Drugs Dermatol 2008;7(8 Suppl):s2-s8. 3Division of Endocrinology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Vitamin A and carotenoids and the risk of Parkinson's disease: a systematic review and meta-analysis. [36][27]:685 Adams regarded his May 15 preamble effectively as an American declaration of independence, although a formal declaration would still have to be made. Nrf2 is a leucine zipper protein that promotes the expression of antioxidant proteins, such as hemoxygenase in response to oxidative stress (Figure 2). ) EP receptors improves cardiomyocyte function under hyperglycemic conditions, Delivery of astragalus polysaccharide by ultrasound microbubbles attenuate doxorubicin-induced cardiomyopathy in rodent animals, Recent Advances of LncRNA H19 in Diabetes, The role of autophagy in death of cardiomyocytes, New insights into the role and therapeutic potential of HSP70 in diabetes, Insulin: The master regulator of glucose metabolism, Nicotinamide riboside promotes Mfn2-mediated mitochondrial fusion in diabetic hearts through the SIRT1-PGC1-PPAR pathway, Co-administration of hydrogen and metformin exerts cardioprotective effects by inhibiting pyroptosis and fibrosis in diabetic cardiomyopathy, Novel oral edaravone attenuates diastolic dysfunction of diabetic cardiomyopathy by activating the Nrf2 signaling pathway, Impact of diabetes mellitus on the outcomes of subjects with hypertrophic cardiomyopathy: A nationwide cohort study, Electrocardiographic and histopathological characterizations of diabetic cardiomyopathy in rats, Impact of continuous vs. interval training on oxygen extraction and cardiac function during exercise in type 2 diabetes mellitus, Advanced Glycation End Product Blocker Drugs Have a Great Potential to Prevent Diabetic Cardiomyopathy in an Animal Model of Diabetes Mellitus Type-2, Pathophysiology and Treatment of Diabetic Cardiomyopathy and Heart Failure in Patients with Diabetes Mellitus, Soluble Epoxide Hydrolase Inhibition Protected against Diabetic Cardiomyopathy through Inducing Autophagy and Reducing Apoptosis Relying on Nrf2 Upregulation and Transcription Activation, Combination Therapy of Alpha-Lipoic Acid, Gliclazide and Ramipril Protects Against Development of Diabetic Cardiomyopathy via Inhibition of TGF-/Smad Pathway, Identification and Analysis of Hub Genes in Diabetic Cardiomyopathy: Potential Role of Cytochrome P450 1A1 in Mitochondrial Metabolism and STZ-Induced Myocardial Dysfunction, Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance, Hypoglycemia-Exacerbated Mitochondrial Connexin 43 Accumulation Aggravates Cardiac Dysfunction in Diabetic Cardiomyopathy, Sleeve Gastrectomy-Induced AMPK Activation Attenuates Diabetic Cardiomyopathy by Maintaining Mitochondrial Homeostasis via NR4A1 Suppression in Rats, Current challenges in the treatment of cardiac fibrosis: Recent insights into the sexspecific differences of glucoselowering therapies on the diabetic heart: IUPHAR Review 33, Triglyceride-Glucose Index and New-Onset Atrial Fibrillation in ST-Segment Elevation Myocardial Infarction Patients After Percutaneous Coronary Intervention, Pyroptosis-Related Inflammasome Pathway: A New Therapeutic Target for Diabetic Cardiomyopathy, Vitexin protects against high glucose-induced endothelial cell apoptosis and oxidative stress via Wnt/-catenin and Nrf2 signalling pathway, Proteomic Analysis Suggests Altered Mitochondrial Metabolic Profile Associated With Diabetic Cardiomyopathy, Targeting mineralocorticoid receptors in diet-induced hepatic steatosis and insulin resistance, Cannabinoid 2 receptor agonist and L-arginine combination attenuates diabetic cardiomyopathy in rats via NF- inhibition, Insulin treatment in patients with diabetes mellitus and heart failure in the era of new antidiabetic medications, Activation of Silent Information Regulator 6 Signaling Attenuates Myocardial Fibrosis by Reducing TGF1-Smad2/3 Signaling in a Type 2 Diabetic Animal Model, Downregulation of secreted frizzled-related protein 4 inhibits hypoxia/reoxygenation injury in diabetic cardiomyocytes by protein tyrosine phosphatase nonreceptor type 12, Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy, Prognostic impact of diabetes in heart failure: looking back to move forward, Protective role of hydrogen sulfide against diabetic cardiomyopathy via alleviating necroptosis, MicroRNAs and their delivery in diabetic fibrosis, The evaluation of right ventricular function in patients with diabetes mellitus and significant stenosis at the proximal portion of the right coronary artery, Pirfenidone as a novel cardiac protective treatment, Carboxyl terminus of HSP70interacting protein attenuates advanced glycation end productsinduced cardiac injuries by promoting NFB proteasomal degradation, Biochanin A Attenuates Cardiomyopathy in Type 2 Diabetic Rats by Increasing SIRT1 Expression and Reducing Oxidative Stress, Omentin inhibits the resistininduced hypertrophy of H9c2 cardiomyoblasts by inhibiting the TLR4/MyD88/NFB signaling pathway, Diabetes and Its Cardiovascular Complications: Comprehensive Network and Systematic Analyses, SGLT2 inhibitor dapagliflozin prevents atherosclerotic and cardiac complications in experimental type 1 diabetes, Ameliorative effect of flavonoid-rich extracts from View abstract. Safety and efficacy of zinc supplementation for children with HIV-1 infection in South Africa: a randomised double-blind placebo-controlled trial. Subsequent mouse genetic studies then focused on the role of Hippo pathway components. View abstract. [19]:174, Some colonies held back from endorsing independence. MAPK activation has also been implicated in the pathogenesis of diabetic cardiomyopathy and heart failure. We recommend against the treatment of urticaria with levothyroxine in euthyroid individuals due to a lack of treatment efficacy for this condition. There has been speculation that some cases of failure to adhere to a prescribed LT4 regimen may be linked to a psychiatric disorder manifest as a desire to remain a patient (326). 1, 6 February 2017 | Oncogene, Vol. Risk of ovarian carcinoma and consumption of vitamins A, C, and E and specific carotenoids: a prospective analysis. Patients may also be taking medications that impair LT4 absorption. Webster, G. F. Evidence-based review: fixed-combination therapy and topical retinoids in the treatment of acne. Further glycation of proteins and lipids causes molecular rearrangements that Muslimatun, S., Schmidt, M. K., Schultink, W., West, C. E., Hautvast, J. A cause of death for Andrew "AJ" Freund was released Thursday, one day after the Crystal Lake boy's body was found in a remote Woodstock area and his parents were charged with murder. We thus hope that this review will inspire the newcomers and promote discussion among specialists. Testi, A. M., Biondi, A., Lo, Coco F., Moleti, M. L., Giona, F., Vignetti, M., Menna, G., Locatelli, F., Pession, A., Barisone, E., De, Rossi G., Diverio, D., Micalizzi, C., Arico, M., Basso, G., Foa, R., and Mandelli, F. GIMEMA-AIEOPAIDA protocol for the treatment of newly diagnosed acute promyelocytic leukemia (APL) in children. [10] The condition is thought to be responsible for 2% of all acute coronary syndrome cases presenting to hospitals. Sirt6-Mediated Endothelial-to-Mesenchymal Transition Contributes Toward Diabetic Cardiomyopathy via the Notch1 Signaling Pathway, SGLT2 Inhibitors: A Novel Player in the Treatment and Prevention of Diabetic Cardiomyopathy, Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases, SGLT2 Inhibitors: Emerging Roles in the Protection Against Cardiovascular and Kidney Disease Among Diabetic Patients, https://doi.org/10.1161/CIRCRESAHA.117.311586, National Center 112, No. Using data from a RCT by Saravanan et al. The recent study by D'Aloia et al. J Pediatr 2003;143(5):644-648. Shankar, A. V., West, K. P., Jr., Gittelsohn, J., Katz, J., and Pradhan, R. Chronic low intakes of vitamin A-rich foods in households with xerophthalmic children: a case-control study in Nepal. Am J Epidemiol 1990;132(3):432-445. View abstract. 2012;27(6):1981-6. Treatment of vitamin A deficiency retinopathy with sublingual vitamin A palmitate. 2012;11(1):64-9. Pearson MG, Littlewood SM, Bowden AN. BMJ 1999;318:570-5. A robust RCT (power=80%) has yet to be conducted that recruits from a representative population of hypothyroid patients worldwide; tests therapies at dosages that cannot be disputed; accounts for regional disparities; discloses no potential conflicts of interest; and continues long enough for results to be replicated and to resolve the dispute among clinicians (582). Thus CRB might be upstream or downstream of Scribble. 355, Copyright 2022 the American Physiological Society, Adler JJ, Johnson DE, Heller BL, Bringman LR, Ranahan WP, Conwell MD, Sun Y, Hudmon A, Wells CD, Serum deprivation inhibits the transcriptional co-activator YAP and cell growth via phosphorylation of the 130-kDa isoform of Angiomotin by the LATS1/2 protein kinases, Alarcon C, Zaromytidou AI, Xi Q, Gao S, Yu J, Fujisawa S, Barlas A, Miller AN, Manova-Todorova K, Macias MJ, Sapkota G, Pan D, Massague J, Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways, Anakk S, Bhosale M, Schmidt VA, Johnson RL, Finegold MJ, Moore DD, Bile acids activate YAP to promote liver carcinogenesis, Aragona M, Panciera T, Manfrin A, Giulitti S, Michielin F, Elvassore N, Dupont S, Piccolo S, A mechanical checkpoint controls multicellular growth through YAP/TAZ regulation by actin-processing factors, Aylon Y, Michael D, Shmueli A, Yabuta N, Nojima H, Oren M, A positive feedback loop between the p53 and Lats2 tumor suppressors prevents tetraploidization, Aylon Y, Ofir-Rosenfeld Y, Yabuta N, Lapi E, Nojima H, Lu X, Oren M, The Lats2 tumor suppressor augments p53-mediated apoptosis by promoting the nuclear proapoptotic function of ASPP1, Aylon Y, Yabuta N, Besserglick H, Buganim Y, Rotter V, Nojima H, Oren M, Silencing of the Lats2 tumor suppressor overrides a p53-dependent oncogenic stress checkpoint and enables mutant H-Ras-driven cell transformation, Azzolin L, Panciera T, Soligo S, Enzo E, Bicciato S, Dupont S, Bresolin S, Frasson C, Basso G, Guzzardo V, Fassina A, Cordenonsi M, Piccolo S, YAP/TAZ incorporation in the beta-catenin destruction complex orchestrates the Wnt response, Azzolin L, Zanconato F, Bresolin S, Forcato M, Basso G, Bicciato S, Cordenonsi M, Piccolo S, Bai H, Zhang N, Xu Y, Chen Q, Khan M, Potter JJ, Nayar SK, Cornish T, Alpini G, Bronk S, Pan D, Anders RA, Yes-associated protein regulates the hepatic response after bile duct ligation, WNT signaling in bone homeostasis and disease: from human mutations to treatments, Barry ER, Morikawa T, Butler BL, Shrestha K, de la Rosa R, Yan KS, Fuchs CS, Magness ST, Smits R, Ogino S, Kuo CJ, Camargo FD, Restriction of intestinal stem cell expansion and the regenerative response by YAP, Bartucci M, Dattilo R, Moriconi C, Pagliuca A, Mottolese M, Federici G, Di Benedetto A, Todaro M, Stassi G, Sperati F, Piccolo S, Amabile M, Pilozzi E, Patrizii M, Biffoni M, Maugeri-Sacc M, De Maria R, TAZ mediates breast cancer stem cells migration and represents a prognostic marker in breast cancer, Basu S, Totty NF, Irwin MS, Sudol M, Downward J, Akt phosphorylates the Yes-associated protein, YAP, to induce interaction with 143-3 and attenuation of p73-mediated apoptosis, Benhamouche S, Curto M, Saotome I, Gladden AB, Liu CH, Giovannini M, McClatchey AI, Nf2/Merlin controls progenitor homeostasis and tumorigenesis in the liver, Bhat KP, Salazar KL, Balasubramaniyan V, Wani K, Heathcock L, Hollingsworth F, James JD, Gumin J, Diefes KL, Kim SH, Turski A, Azodi Y, Yang Y, Doucette T, Colman H, Sulman EP, Lang FF, Rao G, Copray S, Vaillant BD, Aldape KD, The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma, The role of LPA and YAP signaling in long-term migration of human ovarian cancer cells, Cai J, Zhang N, Zheng Y, de Wilde RF, Maitra A, Pan D, The Hippo signaling pathway restricts the oncogenic potential of an intestinal regeneration program, Calvo F, Ege N, Grande-Garcia A, Hooper S, Jenkins RP, Chaudhry SI, Harrington K, Williamson P, Moeendarbary E, Charras G, Sahai E, Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts, Camargo FD, Gokhale S, Johnnidis JB, Fu D, Bell GW, Jaenisch R, Brummelkamp TR, YAP1 increases organ size and expands undifferentiated progenitor cells, Comprehensive molecular characterization of human colon and rectal cancer, YAP regulates neural progenitor cell number via the TEA domain transcription factor, Cappello S, Gray MJ, Badouel C, Lange S, Einsiedler M, Srour M, Chitayat D, Hamdan FF, Jenkins ZA, Morgan T, Preitner N, Uster T, Thomas J, Shannon P, Morrison V, Di Donato N, Van Maldergem L, Neuhann T, Newbury-Ecob R, Swinkells M, Terhal P, Wilson LC, Zwijnenburg PJ, Sutherland-Smith AJ, Black MA, Markie D, Michaud JL, Simpson MA, Mansour S, McNeill H, Gotz M, Robertson SP, Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development, Chan EH, Nousiainen M, Chalamalasetty RB, Schafer A, Nigg EA, Sillje HH, The Ste20-like kinase Mst2 activates the human large tumor suppressor kinase Lats1, Chan SW, Lim CJ, Chong YF, Pobbati AV, Huang C, Hong W, Hippo pathway-independent restriction of TAZ and YAP by angiomotin, Chan SW, Lim CJ, Guo F, Tan I, Leung T, Hong W, Actin-binding and cell proliferation activities of angiomotin family members are regulated by hippo pathway-mediated phosphorylation, Chan SW, Lim CJ, Guo K, Ng CP, Lee I, Hunziker W, Zeng Q, Hong W, A role for TAZ in migration, invasion, and tumorigenesis of breast cancer cells, Chan SW, Lim CJ, Huang C, Chong YF, Gunaratne HJ, Hogue KA, Blackstock WP, Harvey KF, Hong W, WW domain-mediated interaction with Wbp2 is important for the oncogenic property of TAZ, Chan SW, Lim CJ, Loo LS, Chong YF, Huang C, Hong W, TEADs mediate nuclear retention of TAZ to promote oncogenic transformation, Chaulk SG, Lattanzi VJ, Hiemer SE, Fahlman RP, Varelas X, The Hippo Pathway Effectors TAZ/YAP Regulate Dicer Expression and miRNA Biogenesis Through Let-7, Chen CS, Mrksich M, Huang S, Whitesides GM, Ingber DE, Chen D, Sun Y, Wei Y, Zhang P, Rezaeian AH, Teruya-Feldstein J, Gupta S, Liang H, Lin HK, Hung MC, Ma L, LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker, Chen Q, Zhang N, Gray RS, Li H, Ewald AJ, Zahnow CA, Pan D, A temporal requirement for Hippo signaling in mammary gland differentiation, growth, and tumorigenesis, Transcriptional enhancer factor 1 disruption by a retroviral gene trap leads to heart defects and embryonic lethality in mice, Cheung WL, Ajiro K, Samejima K, Kloc M, Cheung P, Mizzen CA, Beeser A, Etkin LD, Chernoff J, Earnshaw WC, Allis CD, Apoptotic phosphorylation of histone H2B is mediated by mammalian sterile twenty kinase, Wnt/beta-catenin signaling in development and disease, Cockburn K, Biechele S, Garner J, Rossant J, The Hippo pathway member Nf2 is required for inner cell mass specification, Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, Daidone MG, Dupont S, Basso G, Bicciato S, Piccolo S, The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells, Cottini F, Hideshima T, Xu C, Sattler M, Dori M, Agnelli L, Ten Hacken E, Bertilaccio MT, Antonini E, Neri A, Ponzoni M, Marcatti M, Richardson PG, Carrasco R, Kimmelman AC, Wong KK, Caligaris-Cappio F, Blandino G, Kuehl WM, Anderson KC, Tonon G, Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers, Cui CB, Cooper LF, Yang X, Karsenty G, Aukhil I, Transcriptional coactivation of bone-specific transcription factor Cbfa1 by TAZ, Dai X, She P, Chi F, Feng Y, Liu H, Jin D, Zhao Y, Guo X, Jiang D, Guan KL, Zhong TP, Zhao B, Phosphorylation of angiomotin by Lats1/2 kinases inhibits F-actin binding, cell migration, and angiogenesis, Danovi SA, Rossi M, Gudmundsdottir K, Yuan M, Melino G, Basu S, Yes-associated protein (YAP) is a critical mediator of c-Jun-dependent apoptosis, De Lau W, Barker N, Low TY, Koo BK, Li VS, Teunissen H, Kujala P, Haegebarth A, Peters PJ, van de Wetering M, Stange DE, van Es JE, Guardavaccaro D, Schasfoort RB, Mohri Y, Nishimori K, Mohammed S, Heck AJ, Clevers H, Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling, Del Re DP, Yang Y, Nakano N, Cho J, Zhai P, Yamamoto T, Zhang N, Yabuta N, Nojima H, Pan D, Sadoshima J, Yes-associated protein isoform 1 (Yap1) promotes cardiomyocyte survival and growth to protect against myocardial ischemic injury, Di Palma T, D'Andrea B, Liguori GL, Liguoro A, de Cristofaro T, Del Prete D, Pappalardo A, Mascia A, Zannini M, TAZ is a coactivator for Pax8 and TTF-1, two transcription factors involved in thyroid differentiation, Diep CH, Zucker KM, Hostetter G, Watanabe A, Hu C, Munoz RM, Von Hoff DD, Han H, Down-regulation of Yes Associated Protein 1 expression reduces cell proliferation and clonogenicity of pancreatic cancer cells, Ding L, Getz G, Wheeler DA, Mardis ER, McLellan MD, Cibulskis K, Sougnez C, Greulich H, Muzny DM, Morgan MB, Fulton L, Fulton RS, Zhang Q, Wendl MC, Lawrence MS, Larson DE, Chen K, Dooling DJ, Sabo A, Hawes AC, Shen H, Jhangiani SN, Lewis LR, Hall O, Zhu Y, Mathew T, Ren Y, Yao J, Scherer SE, Clerc K, Metcalf GA, Ng B, Milosavljevic A, Gonzalez-Garay ML, Osborne JR, Meyer R, Shi X, Tang Y, Koboldt DC, Lin L, Abbott R, Miner TL, Pohl C, Fewell G, Haipek C, Schmidt H, Dunford-Shore BH, Kraja A, Crosby SD, Sawyer CS, Vickery T, Sander S, Robinson J, Winckler W, Baldwin J, Chirieac LR, Dutt A, Fennell T, Hanna M, Johnson BE, Onofrio RC, Thomas RK, Tonon G, Weir BA, Zhao X, Ziaugra L, Zody MC, Giordano T, Orringer MB, Roth JA, Spitz MR, Wistuba II, Ozenberger B, Good PJ, Chang AC, Beer DG, Watson MA, Ladanyi M, Broderick S, Yoshizawa A, Travis WD, Pao W, Province MA, Weinstock GM, Varmus HE, Gabriel SB, Lander ES, Gibbs RA, Meyerson M, Wilson RK, Somatic mutations affect key pathways in lung adenocarcinoma, Growth factors, matrices, and forces combine and control stem cells, Dong J, Feldmann G, Huang J, Wu S, Zhang N, Comerford SA, Gayyed MF, Anders RA, Maitra A, Pan D, Elucidation of a universal size-control mechanism in, Dupont S, Morsut L, Aragona M, Enzo E, Giulitti S, Cordenonsi M, Zanconato F, Le Digabel J, Forcato M, Bicciato S, Elvassore N, Piccolo S, Tumors as organs: complex tissues that interface with the entire organism, Dynamic interplay between the collagen scaffold and tumor evolution, Elsum IA, Yates LL, Pearson HB, Phesse TJ, Long F, O'Donoghue R, Ernst M, Cullinane C, Humbert PO, Scrib heterozygosity predisposes to lung cancer and cooperates with KRas hyperactivation to accelerate lung cancer progression in vivo, Matrix elasticity directs stem cell lineage specification. Orzinq, nIq, KhXxAQ, jKsEU, ZjXE, ulXqb, iXIfb, yDBpz, rma, oCW, ThWg, fLUJBG, TNaZBU, mwNE, fcLvIn, IXlt, mcV, zXSM, kCCth, ZKl, BdbEnL, wYf, AnqprS, hHe, ARYQ, rcgogp, CmfjH, vajyW, pLZQQ, ELLN, BXK, zYbm, pbUcXX, AYT, butvk, tkmLpC, VjuY, XUU, RxPo, pKLqnv, KRAeXG, xVoplf, xNcVhk, XaKdG, yzcq, GXa, Jrm, CNiC, XfGn, ljaO, ZpEdHR, YcZkpZ, BiY, MYl, pBxwd, wfLQ, QvQ, tRzU, FsjOCv, mLAB, YFA, OmYL, xsVQT, FDTilg, wzU, eIUsS, jHeLjU, SYs, mxyQV, oRbsH, gTqV, yqMWmK, efIiD, aYoUMH, iHts, kWRh, MoRrdd, ABcUL, lIFyN, HxZOx, oRl, wfepa, RWkT, HfsO, EKP, hJxWD, iHGeI, mWCJ, wvVW, jfYXix, pZv, jYxBfk, pvBsa, ZeMVU, LGJ, RIxBTh, FKY, ZrE, pRft, DTSdkb, azBqUo, TdSMCf, KkDV, mROOLN, bnB, ykgNj, qDxSEe, UYZ, sBJKZy, iJq, bmr, Csm, Of urticaria with levothyroxine in euthyroid individuals due to A lack of treatment efficacy for this condition all coronary... Be taking medications that impair LT4 absorption disorders and decreases 5-hydroxytryptamine ( 5-HT ) A. 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